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SOS1-IN-19

SOS1-IN-19

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SKU:QM-0013664

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  • Description

    SOS1-IN-19 (Compound 10i) is a potent inhibitor of SOS1 (Son of Sevenless 1) with an IC50 value of 165.2 nM. SOS1-IN-19 blocks KRAS activation by preventing GDP/GTP exchange in KRAS signaling pathway. SOS1-IN-19 is promising for research of KRAS-driven cancers (e.g., NSCLC and colorectal cancer) [1].

  • Molecular Formula

    C24H29F3N6O2

  • Molecular Weight

    490.52

  • Smiles

    COC1=C(OC)C=C2C(N=C(N3CC(N(C)C)C3)N=C2N[C@H](C)C4=CC(N)=CC(C(F)(F)F)=C4)=C1

  • Target

    SOS1

  • Shipping Conditions

    Room temperature

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SOS1-IN-19

SOS1-IN-19 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.