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SOS1-IN-19
SOS1-IN-19
SKU:QM-0013664
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Product Details
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Description
SOS1-IN-19 (Compound 10i) is a potent inhibitor of SOS1 (Son of Sevenless 1) with an IC50 value of 165.2 nM. SOS1-IN-19 blocks KRAS activation by preventing GDP/GTP exchange in KRAS signaling pathway. SOS1-IN-19 is promising for research of KRAS-driven cancers (e.g., NSCLC and colorectal cancer) [1].
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Molecular Formula
C24H29F3N6O2
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Molecular Weight
490.52
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Smiles
COC1=C(OC)C=C2C(N=C(N3CC(N(C)C)C3)N=C2N[C@H](C)C4=CC(N)=CC(C(F)(F)F)=C4)=C1
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Target
SOS1
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Shipping Conditions
Room temperature
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SOS1-IN-19
SOS1-IN-19 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.