α-Spinasterol [CAS 481-18-5]

α-Spinasterol is an orally taken antagonist of transient receptor potential vanilloid 1 (TRPV1), and it's also an inhibitor of COX-1 and COX-2, with IC50 values of 16.17 μM and 7.76 μM, respectively. α-Spinasterol exhibits antibacterial, anti-inflammatory, antidepressant, and antioxidant effects, has the ability to cross the blood-brain barrier, and can improve diabetes in mice[1][2][3][4][5][6].

[481-18-5]

C29H48O

412.69

CC[C@@H](C(C)C)/C=C/[C@@H](C)[C@H]1CC[C@@]2([H])C3=CC[C@@]4([H])C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C

Bacterial; COX; TRP Channel

COX-1; COX-2

99.15

DMF : 2 mg/mL (ultrasonic; warming; heat to 60°C)

4°C (Powder, protect from light)

Room Temperature