Spironolactone-d3

Spironolactone-d3 is the deuterium labeled Spironolactone. Spironolactone (SC9420) is an orally active aldosterone mineralocorticoid receptor antagonist with an IC50 of 24 nM. Spironolactone is also a potent antagonist of androgen receptor with an IC50 of 77 nM. Spironolactone promotes autophagy in podocytes[1][2][3].

C24H29D3O4S

419.59

C[C@@]12[C@@]3(OC(CC3)=O)CC[C@@]1([H])[C@@]4([H])[C@]([C@@]5(C(C[C@H]4SC(C([2H])([2H])[2H])=O)=CC(CC5)=O)C)([H])CC2

Androgen Receptor; Autophagy; Isotope-Labeled Compounds; Mineralocorticoid Receptor

99.82

DMSO : 50 mg/mL (ultrasonic; warming)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature