Spironolactone-d7

Spironolactone-d7 is the deuterium labeled Spironolactone. Spironolactone (SC9420) is an orally active aldosterone mineralocorticoid receptor antagonist with an IC50 of 24 nM. Spironolactone is also a potent antagonist of androgen receptor with an IC50 of 77 nM. Spironolactone promotes autophagy in podocytes[1][2][3].

C24H25D7O4S

423.62

C[C@@]12[C@@]3(OC(C([2H])([2H])C3)=O)CC[C@@]1([H])[C@@]4([H])[C@]([C@@]5(C(C([2H])[C@@]4([2H])SC(C)=O)=C([2H])C(C([2H])([2H])C5)=O)C)([H])CC2

Androgen Receptor; Autophagy; Calcium Channel; Isotope-Labeled Compounds; Mineralocorticoid Receptor

99.96

10 mM in DMSO

-20°C, 3 years (Powder)

Blue Ice