Spore germination-IN-1 (Compound 110) is an orally active spore germination inhibitor (IC50: 14 μM) . Spore germination-IN-1 specifically inhibits the enzymatic activities of mature SleC and CspB on spores (Kd: 12 and 8 μM) . Spore germination-IN-1 can be used in studies against C. difficile[1].