SPP-002

SPP-002 is a sulfate analogue that acts as a potential Sialyltransferase (ST) inhibitor. SPP-002 selectively inhibits n-glycosialylation with inhibition at least an order of magnitude greater than that of unmodified parental cholic acid (LCA) . SPP-002 reduces tumor cell migration and invasion by inhibiting the integrin /FAK/Paxillin signaling pathway. SPP-002 can be used in the study of tumor metastasis[1].

C24H41KO5S

480.74

C[C@H](CCCOS(=O)(O[K])=O)[C@H]1CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C

Sialyltransferase

98

DMSO : ≥ 25 mg/mL

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature