SPR38

SPR38 is a potent SARS-CoV-2 main protease inhibitor, with a Ki of 0.260 μM. SPR38 also inhibits hCatL and hCatB, with Ki values of 1.92 μM and 11.1 μM, respectively[1].

C24H33N3O5

443.54

O=C(OCC1=CC=CC=C1)N[C@@H](CCCC)C(N[C@H](/C=C/C(C)=O)C[C@H]2C(NCC2)=O)=O

Cathepsin; SARS-CoV

Cathepsin B; Cathepsin L

10 mM in DMSO

Room temperature