SQ-33600 [CAS 133983-25-2]

SQ-33600 is an HMG-CoA reductase inhibitor. SQ-33600 has cholesterol-lowering activity. SQ-33600 possesses cell-type selectivity, with much higher inhibitory activity on rat hepatocytes (IC50: 93 nM) than on human skin fibroblasts (IC50: 14200 nM) . SQ-33600 can be used in the research of diseases such as hypercholesterolemia[1][2].

[133983-25-2]

C23H21FNNa2O5P

487.37

O=C(C[C@@H](CP(C#CC(N1C2=CC=C(C=C2)F)=C(C3=C1C=CC=C3)C(C)C)(O[Na])=O)O)O[Na]

HMG-CoA Reductase (HMGCR)

Room temperature