SR 47063 [CAS 135809-60-8]

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SKU:QM-0016553

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Description
SR 47063 is an ATP-sensitive potassium channel (KATP) agonist. SR 47063 selectively activates KATP channels in vascular smooth muscle cells (IC50: 8.1 nM in human saphenous vein, 3.86 nM in rat aorta) . SR 47063 promotes potassium efflux and cellular hyperpolarization to induce vasorelaxation. SR 4706 is promising for research of hypertension and related cardiovascular disorders[1].
CAS Number
[135809-60-8]
Molecular Formula
C17H14N4O3
Molecular Weight
322.32
Smiles
N#C/N=C1C=CC=CN\1C2=CC(C)(C)OC3=C2C=C([N+]([O-])=O)C=C3
Target
Potassium Channel
Shipping Conditions
Room temperature

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SR 47063 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.