SRG-II-19F

SRG-II-19F (dCym-JQ1) is a bromodomain1 of BRDT (BRDTBD1) PROTAC degrader. SRG-II-19F can be used for testing the regulatory effect of ClpC2 on the ClpC1P1P2 protease[1].

C80H109ClN16O14S

1586.34

O=C(NCCOCCOCCOCCOCCN1N=NC(CN2C=C(C[C@@H](C(N(C)[C@@H](C[C@@H](C)CO)C(N[C@@H](C)C(N[C@@H]([C@H](OC)C3=CC=CC=C3)C(N[C@@H](C(C)C)C(N(C)[C@@H](CC(C)C)C(N[C@H]4C(C)C)=O)=O)=O)=O)=O)=O)NC4=O)C5=C2C=CC=C5)=C1)C[C@H]6C7=NN=C(C)N7C8=C(C(C)=C(C)S8)C(C9=CC=C(Cl)C=C9)=N6

Epigenetic Reader Domain; PROTACs

10 mM in DMSO

Room temperature