STAD 2 [CAS 1542100-77-5]

STAD 2 is a potent and selective disruptor of PKA-RII, with a Kd of 6.2 nM. STAD 2 disrupts interactions between PKA and AKAP in an isoform-selective manner. STAD 2 displays antimalarial activity through a PKA-independent mechanism[1][2].

[1542100-77-5]

C102H182N24O22

2096.68

CC(C)C[C@H](NC([C@H](C)NC([C@]1(C)CCC/C=C/CCC[C@](C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N1)=O)=O)=O)=O)(C)NC([C@H](CO)NC([C@@H](NC([C@H](CC(C)C)NC([C@H](CC2=CC=CC=C2)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CCCCN)NC([C@H](CCCCN)NC(COCCOCCOCCN)=O)=O)=O)=O)=O)=O)=O)=O)C(C)C)=O)=O)=O)=O)C(N[C@@H](CCCCN)C(N)=O)=O

PKA

99.55

DMSO : ≥ 100 mg/mL

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

Blue Ice