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SKU:QM-0141100-01
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Stenoparib (E7449) is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC50s of 2.0, 1.0, ~50 and ~50 nM for PARP1, PARP2, TNKS1 and TNKS2, respectively, using 32P-NAD+ as substrate.
[1140964-99-3]
C18H15N5O
317.34
O=C1NNC2=C3C1=CC=CC3=NC(CN4CC5=C(C=CC=C5)C4)=N2
PARP
PARP1; PARP2; TNKS1/PARP5A; TNKS2/PARP5B
98
DMSO : 6.4 mg/mL (ultrasonic; warming)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
H302, H372, H400, H410
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Stenoparib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.