Strontium Ranelate [CAS 135459-87-9]

Strontium Ranelate (S12911) is an antiosteoporotic agent that acts by reducing bone resorption and promoting bone formation, thereby inducing a positive bone balance. Strontium Ranelate can also activate the calcium-sensing receptor (CaSR) in non skeletal cells, resulting in the activation of inositol 1, 4, 5-triphosphate production and mitogen-activated protein kinase signaling[1][2].

[135459-87-9]

C12H6N2O8SSr2

513.49

O=C(O[Sr]OC(C1)=O)C2=C1C(C#N)=C(N3CC(O[Sr]OC(C3)=O)=O)S2

CaSR

99.99

0.1 M HCl : 17.5 mg/mL (ultrasonic; adjust pH to 3 with HCl) |H2O : 2 mg/mL (ultrasonic; warming; heat to 60°C)

4°C (Powder, sealed storage, away from moisture)

Room Temperature

H302, H315, H319, H335

H302, H315, H319, H335