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STX107 [CAS 935685-90-8]
STX107 [CAS 935685-90-8]
SKU:QM-0052158
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Product Details
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Description
STX107 is a metabotropic glutamate 5 (mGlu5) receptor negative allosteric modulator (NAM) with a pKi of 8.32. STX107 inhibits glutamate-induced Ca2+ mobilization, IP1 accumulation, and ERK1/2 phosphorylation. STX107 also inhibits glutamate-induced mGlu5 internalization[1].
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CAS Number
[935685-90-8]
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Molecular Formula
C18H10FN3S
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Molecular Weight
319.36
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Smiles
N#CC1=CC(F)=CC(C2=NC=C(C=C2)C#CC3=CSC(C)=N3)=C1
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Target
ERK; mGluR
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Isoform
MGluR5
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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STX107 [CAS 935685-90-8]
STX107 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.