SU11606 [CAS 669764-17-4]

SU11606 is a Met inhibitor, with an average IC50 of 0.17 μM. SU11606 shows inhibitory activity on Ron, FLK-1, with IC50s of 2.5 μM and 0.18 μM, respectively. SU11606 can be used in the research of tumors[1].

[669764-17-4]

C29H33ClN4O4S

569.11

O=S(C1=CC2=C(C=C1)NC(/C2=C\C3=C(C(CCCN4CCOCC4)=C(N3)C)C)=O)(N(C)C5=CC=CC(Cl)=C5)=O

C-Met/HGFR; VEGFR

VEGFR2/KDR/Flk-1

Room temperature