Subquinocin

Subquinocin is a CYLD inhibitor that inhibits USP family deubiquitinases (DUBs) . Subquinocin enhances the activation of NF-κB and IFN pathways by inhibiting CYLD. Subquinocin promotes RIG-I-mediated activation of IRF3 and/or IRF7 in the interferon pathway[1].

C20H27N3O4S

405.51

O=C1N(CC(C)C)C=C(NC(NC(CCSC)C(OC)=O)=O)C2=C1C=CC=C2

Deubiquitinase; IFNAR; NF-κB

99.83

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature