(-) -Syringaresinol [CAS 6216-81-5]

(-) -Syringaresinol is an orally active isomer of syringaresinol found in Annona Montana. (-) -Syringaresinol exhibits antioxidant, anti-inflammatory, and anticancer activities. (-) -Syringaresinol can alleviate ulcerative colitis via the PI3K-Akt/MAPK/Wnt signaling pathway. (-) -Syringaresinol inhibits HL-60 cell proliferation by arresting the G1 phase and inducing apoptosis. (-) -Syringaresinol inhibits LPS (HY-D1056) -induced microglial activation by downregulating the NF-κB p65 signaling pathway and its interaction with ERβ, exerting anti-neuroinflammatory effects[1][2][3].

[6216-81-5]

C22H26O8

418.44

OC1=C(OC)C=C([C@@H]2OC[C@]3([H])[C@@]2([H])CO[C@H]3C4=CC(OC)=C(O)C(OC)=C4)C=C1OC

Akt; Apoptosis; Bcl-2 Family; CD20; CDK; COX; Drug Isomer; GSK-3; IFNAR; Interleukin Related; NF-κB; NO Synthase; p38 MAPK; TNF Receptor

99.93

DMSO : 100 mg/mL (ultrasonic)

4°C (Powder, protect from light)

Room Temperature