T-Boc-N-amido-PEG4-Val-Cit [CAS 2231240-82-5]
T-Boc-N-amido-PEG4-Val-Cit [CAS 2231240-82-5]
SKU:QM-0054842
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Product Details
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Description
T-Boc-N-amido-PEG4-Val-Cit is a protease-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit dipeptide. The Val-Cit dipeptide is cleavable by cell proteases and features a carboxylic acid which is free for coupling reactions with amines to form amides. The Boc can be removed under acidic conditions to reveal a free primary amine, which may be used in a variety of reactions such as coupling or reductive amination.
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CAS Number
[2231240-82-5]
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Molecular Formula
C27H51N5O11
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Molecular Weight
621.72
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Smiles
NC(NCCC[C@@H](C(O)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCNC(OC(C)(C)C)=O)=O)=O)=O
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Target
ADC Linker
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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T-Boc-N-amido-PEG4-Val-Cit [CAS 2231240-82-5]
T-Boc-N-amido-PEG4-Val-Cit is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.