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Taletrectinib [CAS 1505515-69-4]

Taletrectinib [CAS 1505515-69-4]

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QM-0143483-01

£294.22 GBP
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Product Details

  • Description

    Taletrectinib (DS-6051b) is a potent, orally active, and next-generation selective ROS1/NTRK inhibitor. Taletrectinib potently inhibits recombinant ROS1, NTRK1, NTRK2, and NTRK3 with IC50s of 0.207, 0.622, 2.28, and 0.98 nM, respectively. Taletrectinib also inhibits ROS1 G2032R and other Crizotinib-resistant ROS1 mutants[1][2].

  • CAS Number

    [1505515-69-4]

  • Molecular Formula

    C29H34FN5O5

  • Molecular Weight

    551.61

  • Smiles

    O=C(O)CCCCC(O)=O.C[C@@H](NC1=NN2C(C=C1)=NC=C2C3=CC=C(OC[C@H](N)C)C=C3)C4=CC=CC(F)=C4

  • Target

    ROS Kinase

  • Purity

    99.78

  • Solubility

    DMSO : 50 mg/mL (ultrasonic)

  • Storage Conditions

    4°C (Powder, sealed storage, away from moisture)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
5 mgQM-0143483-01
5 mgQM-0143483-01
£294.22/ea		 £0.00
£294.22/ea £0.00
10 mM - 1 mLQM-0143483-02
10 mM - 1 mLQM-0143483-02
£347.68/ea		 £0.00
£347.68/ea £0.00
10 mgQM-0143483-03
10 mgQM-0143483-03
£438.80/ea		 £0.00
£438.80/ea £0.00
25 mgQM-0143483-04
25 mgQM-0143483-04
£672.08/ea		 £0.00
£672.08/ea £0.00
50 mgQM-0143483-05
50 mgQM-0143483-05
£922.37/ea		 £0.00
£922.37/ea £0.00
100 mgQM-0143483-06
100 mgQM-0143483-06
£1,279.58/ea		 £0.00
£1,279.58/ea £0.00
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Taletrectinib [CAS 1505515-69-4]

Taletrectinib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.