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Taminadenant (mesylate) [CAS 2253894-81-2]

Taminadenant (mesylate) [CAS 2253894-81-2]

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SKU:QM-0087845

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  • Description

    Taminadenant mesylate (NIR178 mesylate) is a potent adenosine A2A receptor antagonist with potential anti-tumor activity. Taminadenant mesylate can selectively bind and inhibit A2AR on T lymphocytes, thereby releasing adenosine/A2AR-mediated inhibition of T lymphocytes and activating T cell-mediated immune responses against tumor cells. Taminadenant mesylate works by reducing the proliferation of susceptible tumor cells. Taminadenant mesylate also showed effectiveness in reversing dyskinesias in Parkinson's disease models and was able to inhibit dyskinesias caused by L-DOPA[1].

  • CAS Number

    [2253894-81-2]

  • Molecular Formula

    C11H12BrN7O3S

  • Molecular Weight

    402.23

  • Smiles

    BrC(C(N1C=CC=N1)=NC(N2C=CC=N2)=N3)=C3N.O=S(O)(C)=O

  • Target

    Adenosine Receptor

  • Shipping Conditions

    Room temperature

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Taminadenant (mesylate) [CAS 2253894-81-2]

Taminadenant (mesylate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.