Tauromustine [CAS 85977-49-7]

Tauromustine is an orally active nitrosourea anticancer agent. Tauromustine has an alkylation effect and can damage the DNA function. Tauromustine has a high therapeutic index, especially in the treatment of Walker 256 rat sarcoma. It is also active against melanoma, breast cancer, pleural mesothelioma and ovarian cancer. Tauromustine is mainly metabolized in the liver, but some of its metabolites also have cytotoxicity[1][2][3].

[85977-49-7]

C7H15ClN4O4S

286.74

O=NN(CCCl)C(NCCS(=O)(N(C)C)=O)=O

DNA/RNA Synthesis

Room temperature