TB-21007 [CAS 207306-50-1]

TB-21007 is a selective and brain penetrant α5 subunit-containing GABAA receptor inverse agonist with Kis of 1.6 nM, 20 nM, 16 nM, and 20 nM for α5, α1, α2 and α3 subtypes, respectively. TB-21007 enhances cognition in rats[1].

[207306-50-1]

C15H17NO2S3

339.5

O=C1CC(C)(C)CC2=C(C3=NC=CS3)SC(SCCO)=C21

GABA Receptor

99.7

DMSO : 40 mg/mL (ultrasonic; warming)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature