TBK1-IN-1

TBK1-IN-1 is a potent and selective TANK binding kinase 1 (TBK1) inhibitor with an IC50 value of 22.4 nM. TBK1-IN-1 inhibits TBK1 downstream target genes cxcl10 and ifnβ expression. TBK1-IN-1 has anticancer activity[1].

C27H35N7O2

489.61

CC(N1CCN(CC1)CC2=CC=CC(NC3=NC=C4C=CN(C4=N3)CCCNC(C5CCC5)=O)=C2)=O

IKK

TBK1

99.91

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature