TC-PTP-IN-1 [CAS 1187396-28-6]

TC-PTP-IN-1 (compound 8) is a potent TC-PTP inhibitor with an IC50 value of 9.2 nM, Ki values of 4.3, 34 nM for TC-PTP, PTP1B, respectively. TC-PTP-IN-1 increases the protein expression of pSre416[1]. TC-PTP-IN-1 (compound 3) is the TC-PTP Ligand of TP1L.

[1187396-28-6]

C46H62F2N5O9P

897.98

O=P(O)(O)C(F)(F)C(C=C1)=CC=C1C[C@@H](C(N[C@H](C(N)=O)CCCCNC(C2=CC=C(C=C2)CC)=O)=O)NC([C@@H](NC(CO[C@@H]3[C@H](CC[C@@H](C3)C)C(C)C)=O)CC4=CC=CC=C4)=O

Phosphatase

Room temperature