TCMCB07 (TFA)

TCMCB07 TFA, a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 TFA plays an important role in cachexia[1].

C63H87N15O11.xC2HF3O2

N/C(N)=N/CCC[C@@H](C(N[C@@H](CC1=CNC2=C1C=CC=C2)C(N[C@H](C(NC(C(N3[C@@H](C(N)=O)CCC3)=O)C(C)C)=O)CCCCNC(C[C@@H]4NC([C@H](CCCC)NC(C)=O)=O)=O)=O)=O)NC([C@@H](CC5=CC=C(C=CC=C6)C6=C5)NC([C@H](CCC7)N7C4=O)=O)=O.OC(C(F)(F)F)=O.[x]

Melanocortin Receptor

99.69

DMSO : ≥ 100 mg/mL

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

Blue Ice