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TEAD-IN-9
TEAD-IN-9
SKU:QM-0092391
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Product Details
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Description
TEAD-IN-9 (compound 17) is a TEAD1 inhibitor with an IC50 of 0.29 μM. TEAD-IN-9 targets the palmitoyl pocket of TEAD, thereby effectively inhibiting the binding of YAP-TEAD and blocking the transcriptional function of YAP-TEAD[1].
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Molecular Formula
C23H23F3N3O3P
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Molecular Weight
477.42
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Smiles
O=P(C)(C)C1=CC=C(NCC2=CC=C(C(F)(F)F)C=C2)C(C3=NC(OC4COC4)=CC=N3)=C1
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Target
YAP
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Isoform
TEAD
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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TEAD-IN-9
TEAD-IN-9 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.