Tegeprotafib (PTPN2/1-IN-1) (Compound 124) is an orally active PTPN1 and PTPN2 inhibitor with IC50s of 4.4 nM and 1-10 nM against PTPN2 and PTP1B, respectively[1].
CAS Number
[2407610-46-0]
Molecular Formula
C13H11FN2O5S
Molecular Weight
326.3
Smiles
O=C1NS(=O)(N(C1)C2=C(F)C3=CC(OC)=CC=C3C=C2O)=O
Target
Phosphatase
Purity
99.3
Solubility
DMSO : 100 mg/mL (ultrasonic)
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)