Tetrazine-biotin [CAS 1714123-51-9]

Tetrazine-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Tetrazine-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

[1714123-51-9]

C19H23N7O2S

413.5

O=C(NCC1=CC=C(C2=NN=CN=N2)C=C1)CCCC[C@@H]3SC[C@]([C@]3([H])N4)([H])NC4=O

ADC Linker

Cleavable Linker

98

DMSO : 50 mg/mL (ultrasonic)

-20°C (Powder, stored under nitrogen)

Blue Ice

H315, H319

H315, H319