TFSeB [CAS 3017240-62-6]

TFSeB is an orally active neuroprotective agent. TFSeB can reduce Streptozotocin (STZ) induced MAO-B and AChE activity. TFSeB exerts neuroprotective effects by increasing the expression of BCL-2, BDNF, NRF2, and decreasing the expression of BAX. TFSeB can reduce lipid peroxidation (TBARS) and reactive oxygen species (ROS) levels. TFSeB can reduce neuroinflammation. TFSeB can be used for research on Alzheimer’s disease[1].

[3017240-62-6]

C16H13F3OSe

357.23

FC(F)(C1=CC=CC([Se]CC2CC3=C(O2)C=CC=C3)=C1)F

Bcl-2 Family; Cholinesterase (ChE) ; Monoamine Oxidase; NF-κB; Reactive Oxygen Species (ROS)

AChE; Bax; Bcl-2

Room temperature