TH16

TH16 is an antibacterial agent (MIC=2 μg/mL against methicillin-resistant Staphylococcus aureus, MRSA) . TH16 disrupts bacterial cytoplasmic membrane integrity, elevating intracellular reactive oxygen species (ROS) levels to induce bacterial death. TH16 is promising for research of bacterial infection[1].

C42H42BrO3P

705.66

C=CCC1=CC=C(C(C2=CC=C(C(CC=C)=C2)O)=C1)OC(CCCCC[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)=O.[Br-]

Bacterial; Reactive Oxygen Species (ROS)

Room temperature