Thalidomide-5-NH2-6-F [CAS 2995272-75-6]

Thalidomide-5-NH2-6-F is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-5-NH2-6-F can be linked to a target protein ligand via a linker to form a PROTAC.

[2995272-75-6]

C13H10FN3O4

291.24

O=C1NC(=O)C(N2C(=O)C3=CC(F)=C(N)C=C3C2=O)CC1

Ligands for E3 Ligase

Cereblon

Room temperature

H302-H315-H319-H335

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501