1 1

Thalidomide-5-O-CH2-COOH [CAS 2467425-53-0]

Thalidomide-5-O-CH2-COOH [CAS 2467425-53-0]

Size

QM-0204886-01

£36.91 GBP
Sale Sold out

Request quote or documents

View full details

Product Details

  • Description

    Thalidomide-5-O-CH2-COOH is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide and NH-PEG3-NH-Boc. Thalidomide-5-O-CH2-COOH acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide-5-O-CH2-COOH is a key intermediate in the synthesis of PROTAC molecules designed based on CRBN.

  • CAS Number

    [2467425-53-0]

  • Molecular Formula

    C15H12N2O7

  • Molecular Weight

    332.26

  • Smiles

    O=C(O)COC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2=O)=O)C=C1

  • Target

    Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates

  • Isoform

    Cereblon

  • Purity

    97

  • Solubility

    DMSO : 125 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
Learn more
Variant Variant total Quantity Price Variant total
5 mgQM-0204886-01
5 mgQM-0204886-01
£23.40
£36.91/ea
 £0.00
£23.40
£36.91/ea
 £0.00
10 mgQM-0204886-02
10 mgQM-0204886-02
£32.40
£47.26/ea
 £0.00
£32.40
£47.26/ea
 £0.00
25 mgQM-0204886-03
25 mgQM-0204886-03
£60.30
£100.38/ea
 £0.00
£60.30
£100.38/ea
 £0.00
50 mgQM-0204886-04
50 mgQM-0204886-04
£92.70
£140.88/ea
 £0.00
£92.70
£140.88/ea
 £0.00
100 mgQM-0204886-05
100 mgQM-0204886-05
£153.00
£256.55/ea
 £0.00
£153.00
£256.55/ea
 £0.00
View cart
0

Total items

£0.00

Product subtotal

Taxes, discounts and shipping calculated at checkout.
View cart

Related Products

Other industry favorites

Thalidomide-5-O-CH2-COOH [CAS 2467425-53-0]

Thalidomide-5-O-CH2-COOH is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.