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Thalidomide [CAS 50-35-1]

Thalidomide [CAS 50-35-1]

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SKU:QM-0148962-01

£94.75 GBP
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  • Description

    Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ∼250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties. Thalidomide can work as molecular glue to potentiate substrate.

  • CAS Number

    [50-35-1]

  • Molecular Formula

    C13H10N2O4

  • Molecular Weight

    258.23

  • Smiles

    O=C1N(C2CCC(NC2=O)=O)C(C3=CC=CC=C31)=O

  • Target

    Apoptosis; Autophagy; Ligands for E3 Ligase; Molecular Glues

  • Isoform

    Cereblon

  • Purity

    99.98

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H301, H312, H360

  • Precautions

    H301, H312, H360

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200 mgQM-0148962-01
200 mgQM-0148962-01
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10 mM - 1 mLQM-0148962-02
10 mM - 1 mLQM-0148962-02
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500 mgQM-0148962-03
500 mgQM-0148962-03
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Thalidomide [CAS 50-35-1]

Thalidomide is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.