Thalidomide-azetidine-C-PIP-C-boc [CAS 2589699-87-4]
Thalidomide-azetidine-C-PIP-C-boc [CAS 2589699-87-4]
SKU:QM-0102164
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Product Details
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Description
Thalidomide-azetidine-C-PIP-C-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide and the corresponding Linker. Thalidomide-azetidine-C-PIP-C-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
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CAS Number
[2589699-87-4]
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Molecular Formula
C27H35N5O6
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Molecular Weight
525.6
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Smiles
O=C1NC(CCC1N2C(C3=C(C=CC(N4CC(C4)CN5CCN(CC5)CC(OC(C)(C)C)=O)=C3)C2=O)=O)=O
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Target
Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
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Isoform
Cereblon
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Thalidomide-azetidine-C-PIP-C-boc [CAS 2589699-87-4]
Thalidomide-azetidine-C-PIP-C-boc is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.