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Thalidomide-NH-C10-Boc [CAS 2428400-25-1]
Thalidomide-NH-C10-Boc [CAS 2428400-25-1]
SKU:QM-0118898
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Product Details
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Description
Thalidomide-NH-C10-Boc (compound S20) is a conjugate of the E3 ubiquitinase ligand Thalidomide and PROTAC Linker, which can recruit Cereblon ubiquitinase. Thalidomide-NH-C10-Boc can couple the target protein ligand through the PTOTAC Linker to synthesize PROTAC molecules with degradation effects. For example, Thalidomide-NH-C10-Boc can couple with the ligand EP300/CBP ligand 2 to produce the PROTAC molecule dCE-2 (HY-161958).
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CAS Number
[2428400-25-1]
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Molecular Formula
C28H39N3O6
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Molecular Weight
513.63
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Smiles
O=C(N1C2CCC(NC2=O)=O)C3=CC=CC(NCCCCCCCCCCC(OC(C)(C)C)=O)=C3C1=O
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Target
E3 Ligase Ligand-Linker Conjugates
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Shipping Conditions
Room temperature
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Thalidomide-NH-C10-Boc [CAS 2428400-25-1]
Thalidomide-NH-C10-Boc is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.