Thalidomide-NH-C6-NH-Boc [CAS 2093536-13-9]
Thalidomide-NH-C6-NH-Boc [CAS 2093536-13-9]
SKU:QM-0143439-01
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Product Details
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Description
Thalidomide-NH-C6-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used for MI-389 (compound 22) synthesis. MI-389 is a potent phthalimide PROTAC degrader based on the multi-targeted receptor tyrosine kinase inhibitor sunitinib.
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CAS Number
[2093536-13-9]
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Molecular Formula
C24H32N4O6
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Molecular Weight
472.53
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Smiles
O=C(OC(C)(C)C)NCCCCCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
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Target
Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
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Isoform
Cereblon
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Purity
96.11
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Thalidomide-NH-C6-NH-Boc [CAS 2093536-13-9]
Thalidomide-NH-C6-NH-Boc is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.