Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc [CAS 1799711-31-1]
Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc [CAS 1799711-31-1]
SKU:QM-0148430-01
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Product Details
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Description
Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc incorporates the Thalidomide based cereblon ligand and a linker. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc can be used for the synthesis of PROTAC BET degrader[1]. (From patent WO2017180417A1 compound s7) .
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CAS Number
[1799711-31-1]
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Molecular Formula
C30H42N4O11
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Molecular Weight
634.67
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Smiles
O=C(NCCCOCCOCCOCCCNC(COC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)=O)OC(C)(C)C
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Target
Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
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Isoform
Cereblon
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Purity
98.43
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc [CAS 1799711-31-1]
Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.