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Thalidomide-O-C8-Boc [CAS 2225148-52-5]
Thalidomide-O-C8-Boc [CAS 2225148-52-5]
SKU:QM-0143573-01
£94.75 GBP
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Product Details
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Description
Thalidomide-O-C8-Boc is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-C8-Boc can be connected to the ligand for protein by a linker to form PROTACs[1].
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CAS Number
[2225148-52-5]
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Molecular Formula
C26H34N2O7
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Molecular Weight
486.56
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Smiles
O=C(OC(C)(C)C)CCCCCCCCOC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
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Target
Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
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Isoform
Cereblon
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Purity
95.12
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, stored under nitrogen)
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Shipping Conditions
Blue Ice
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Thalidomide-O-C8-Boc [CAS 2225148-52-5]
Thalidomide-O-C8-Boc is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.