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Thalidomide-piperazine- (R) -C-pyrrolidine-C-boc
Thalidomide-piperazine- (R) -C-pyrrolidine-C-boc
SKU:QM-0124723
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Quantity
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Product Details
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Description
Thalidomide-piperazine- (R) -C-pyrrolidine-C-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide and the corresponding Linker. Thalidomide-piperazine- (R) -C-pyrrolidine-C-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
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Molecular Formula
C28H37N5O6
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Molecular Weight
539.62
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Smiles
O=C1NC(CCC1N2C(C3=C(C=CC(N4CCN(CC4)C[C@@H]5CN(CC5)CC(OC(C)(C)C)=O)=C3)C2=O)=O)=O
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Target
Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
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Isoform
Cereblon
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Thalidomide-piperazine- (R) -C-pyrrolidine-C-boc
Thalidomide-piperazine- (R) -C-pyrrolidine-C-boc is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.