Thalidomide-Propargyne-PEG3-COOH [CAS 2797649-54-6]

Thalidomide-Propargyne-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. Thalidomide-Propargyne-PEG3-COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

[2797649-54-6]

C23H24N2O9

472.44

OC(CCOCCOCCOCC#CC(C=C12)=CC=C2C(N(C1=O)C3CCC(NC3=O)=O)=O)=O

Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates

Cereblon

96.25

DMSO : 100 mg/mL (ultrasonic)

-20°C (Powder, sealed storage, away from moisture and light)

Blue Ice