THK-5117 [CAS 1374107-54-6]

Name: THK-5117 [CAS 1374107-54-6]
Brand: QuantiMol
SKU: QM-0057042-01
Price: 884.71 GBP
Availability: InStock

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SKU:QM-0057042-01

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Product Details

Description
THK-5117, an arylquinoline derivative, displays high binding affinity to tau fibrils with a Ki of 10.5 nM. THK-5117 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD) brain homogenates. 18F-THK-5117 has the potential to act as a tau imaging PET probe[1].
CAS Number
[1374107-54-6]
Molecular Formula
C19H19FN2O2
Molecular Weight
326.36
Smiles
OC(COC1=CC=C2N=C(C3=CC=C(NC)C=C3)C=CC2=C1)CF
Target
Microtubule/Tubulin
Purity
98.52
Solubility
10 mM in DMSO
Storage Conditions
4°C (Powder, stored under nitrogen)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0057042-01	5 mgQM-0057042-01 £884.71/ea	£0.00	Quantity	£884.71/ea	£0.00

10 mgQM-0057042-02	10 mgQM-0057042-02 £1,430.24/ea	£0.00	Quantity	£1,430.24/ea	£0.00

25 mgQM-0057042-03	25 mgQM-0057042-03 £3,125.16/ea	£0.00	Quantity	£3,125.16/ea	£0.00

50 mgQM-0057042-04	50 mgQM-0057042-04 £4,380.26/ea	£0.00	Quantity	£4,380.26/ea	£0.00

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THK-5117 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.