Threo-dihydrobupropion [CAS 153365-82-3]

Threo-dihydrobupropion is a major metabolite of Bupropion, formed via oxidation and reduction exhibit pharmacological activity. Bupropion, a dual dopamine-norepinephrine uptake inhibitor and a nicotine receptor antagonist, is widely used in the management of depression and as a smoking cessation aid[1].

[153365-82-3]

C13H20ClNO

241.76

CC(C)(C)N[C@H](C)[C@@H](C1=CC(Cl)=CC=C1)O

Drug Metabolite

10 mM in DMSO

Room temperature