THZ-P1-2 [CAS 2058075-45-7]

Name: THZ-P1-2 [CAS 2058075-45-7]
Brand: QuantiMol
SKU: QM-0145515-01
Price: 301.5 GBP
Availability: InStock

Size 5 mg 10 mM - 1 mL 10 mg 50 mg 100 mg

SKU:QM-0145515-01

£301.50 GBP

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Product Details

Description
THZ-P1-2 is a first-in-class and selective PI5P4K inhibitor, with an IC50 of 190 nM for PI5P4Kα. THZ-P1-2 covalently targets cysteines on a disordered loop in PI5P4Kα/β/γ. THZ-P1-2 causes autophagy disruption and upregulates TFEB signaling. THZ-P1-2 displays anticancer activity in leukemia cell lines[1].
CAS Number
[2058075-45-7]
Molecular Formula
C31H29N7O2
Molecular Weight
531.61
Smiles
O=C(C(C=C1)=CC=C1NC(/C=C/CN(C)C)=O)NC2=CC=CC(NC3=CC(C4=CNC5=CC=CC=C45)=NC=N3)=C2
Target
Autophagy
Purity
99.54
Solubility
DMSO : 100 mg/mL (ultrasonic)
Storage Conditions
4°C (Powder, protect from light)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0145515-01	5 mgQM-0145515-01 £301.50/ea	£0.00	Quantity	£301.50/ea	£0.00

10 mM - 1 mLQM-0145515-02	10 mM - 1 mLQM-0145515-02 £344.03/ea	£0.00	Quantity	£344.03/ea	£0.00

10 mgQM-0145515-03	10 mgQM-0145515-03 £401.13/ea	£0.00	Quantity	£401.13/ea	£0.00

50 mgQM-0145515-04	50 mgQM-0145515-04 £840.97/ea	£0.00	Quantity	£840.97/ea	£0.00

100 mgQM-0145515-05	100 mgQM-0145515-05 £1,156.87/ea	£0.00	Quantity	£1,156.87/ea	£0.00

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THZ-P1-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.