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Timegadine [CAS 71079-19-1]

Timegadine [CAS 71079-19-1]

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QM-0000005

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Product Details

  • Description

    Timegadine, a new antiinflammatory agent, is found to be a potent, competitive inhibitor of cyclo-oxygenase (COX) and lipo-oxygenase, with IC50s ranging from 5 nM (washed rabbit platelets) to 20 μM (rat brain) for COX and 100 μM for lipo-oxygenase both in the cytosol fraction of horse platelet homogenates, and in washed rabbit platelets.

  • CAS Number

    [71079-19-1]

  • Molecular Formula

    C20H23N5S

  • Molecular Weight

    365.5

  • Smiles

    CC1=NC2=CC=CC=C2C(/N=C(NC3CCCCC3)/NC4=NC=CS4)=C1

  • Target

    COX

  • Isoform

    COX

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

  • Hazard Statement

    H302-H315-H319-H335

  • Precautions

    P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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1 EachQM-0000005
1 EachQM-0000005
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Timegadine [CAS 71079-19-1]

Timegadine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.