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TK-684

TK-684

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QM-0011643

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Product Details

  • Description

    TK-684 is a potent and selective allosteric SHP2 inhibitor with IC50 values of 2.1, > 1000 nM for SHP2WT, SHP22PTP, respectively. TK-684 inhibits cell proliferation and induces apoptosis. TK-684 decreases the protein expression of p-AKT, p-ERK[1].

  • Molecular Formula

    C17H21ClN8OS

  • Molecular Weight

    420.92

  • Smiles

    ClC1=C(N=CC=C1SC2=NNC(N=C(N3)N4CCC(C)(CC4)CN)=C2C3=O)N

  • Target

    Apoptosis; SHP2

  • Shipping Conditions

    Room temperature
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Variant Variant total Quantity Price Variant total
1 EachQM-0011643
1 EachQM-0011643
£0.00/ea		 £0.00
£0.00/ea £0.00

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TK-684

TK-684 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.