TK216-d4 [CAS 3034816-36-6]

TK216-d4 is the deuterium labeled TK216. TK216 is an orally active and potent E26 transformation specific (ETS) inhibitor[1]. TK216 directly binds EWS-FLI1 and inhibits EWS-FLI1 protein interactions. TK216 blocks the binding between EWS-FLI1 and RNA helicase A. TK216 has anticancer activity[2].

[3034816-36-6]

C19H11D4Cl2NO3

380.26

O=C1NC2=C(C1(O)CC(C3=C([2H])C([2H])=C(C([2H])=C3[2H])C4CC4)=O)C(Cl)=CC=C2Cl

DNA/RNA Synthesis; Isotope-Labeled Compounds

98.52

-20°C, 3 years (Powder)

Blue Ice