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TMPA [CAS 1258275-73-8]

TMPA [CAS 1258275-73-8]

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QM-0154985-01

£215.24 GBP
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Product Details

  • Description

    TMPA is a high-affinity Nur77 antagonist that binds to Nur77 leading to the release and shuttling of LKB1 in the cytoplasm to activate AMPKα. TMPA effectively lowers blood glucose and attenuates insulin resistance in type II db/db, high-fat diet and streptozotocin-induced diabetic mice. TMPA reduces RICD (restimulation-induced cell death) in human T cells, can also be used in studies of cancer and T-cell apoptosis dysregulation[1][2].

  • CAS Number

    [1258275-73-8]

  • Molecular Formula

    C21H32O6

  • Molecular Weight

    380.48

  • Smiles

    COC1=C(CC(OCC)=O)C(C(CCCCCCC)=O)=CC(OC)=C1OC

  • Target

    AMPK; Nuclear Hormone Receptor 4A/NR4A

  • Isoform

    Nur77/NR4A1

  • Purity

    98.4

  • Solubility

    DMSO : ≥ 100 mg/mL

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319

  • Precautions

    H302, H315, H319
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Variant Variant total Quantity Price Variant total
2 mgQM-0154985-01
2 mgQM-0154985-01
£215.24/ea		 £0.00
£215.24/ea £0.00
5 mgQM-0154985-02
5 mgQM-0154985-02
£319.73/ea		 £0.00
£319.73/ea £0.00
10 mM - 1 mLQM-0154985-03
10 mM - 1 mLQM-0154985-03
£347.68/ea		 £0.00
£347.68/ea £0.00
10 mgQM-0154985-04
10 mgQM-0154985-04
£489.83/ea		 £0.00
£489.83/ea £0.00
50 mgQM-0154985-05
50 mgQM-0154985-05
£1,116.77/ea		 £0.00
£1,116.77/ea £0.00
100 mgQM-0154985-06
100 mgQM-0154985-06
£1,681.74/ea		 £0.00
£1,681.74/ea £0.00
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TMPA [CAS 1258275-73-8]

TMPA is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.