TNF-alpha-IN-1

TNF-alpha-IN-1 (compound 202) is an orally active inhibitor of TNF-alpha. TNF-alpha-IN-1 has anti-inflammatory activity which can used in study rheumatoid arthritis, psoriasis, and asthma[1].

C57H57N5O8

940.09

O=C([C@@H](NC([C@H](NC(CCC(NC1=CC=C(C[C@H](N2)C(N[C@@H](CC3=CC=CC=C3)C(O)=O)=O)C=C1)=O)=O)CCC4=CC=CC=C4)=O)CC5=CC=C(C6=CC=CC=C6)C=C5)C[C@H](CC7=CC=CC=C7)C2=O

TNF Receptor

10 mM in DMSO

Room temperature