TNF-α-IN-19 [CAS 338773-13-0]

Name: TNF-α-IN-19 [CAS 338773-13-0]
Brand: QuantiMol
SKU: QM-0103452-01
Price: 251.69 GBP
Availability: InStock

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SKU:QM-0103452-01

£251.69 GBP

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Product Details

Description
TNF-α-IN-19 is an inhibitor of TNFα that can block the interaction between TNFαRI, TRADD, and RIP1, the EC50 values for TNFα, IL-1β, and IL-1β/TNFα are 2.451, 3.792 and 1.54 μM, respectively. TNF-α-IN-19 only inhibits the degradation of IκBα when cells are stimulated by TNFα and not by IL-1β[1].
CAS Number
[338773-13-0]
Molecular Formula
C16H8ClF3N4
Molecular Weight
348.71
Smiles
ClC1=CC=C(C2=NN=C3N2C4=C(N=C3C(F)(F)F)C=CC=C4)C=C1
Target
IKK; Interleukin Related; RIP kinase; TNF Receptor
Isoform
IL-1
Shipping Conditions
Room temperature

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Variant	Variant total	Quantity	Price	Variant total
1 mgQM-0103452-01	1 mgQM-0103452-01 £251.69/ea	£0.00	Quantity	£251.69/ea	£0.00

5 mgQM-0103452-02	5 mgQM-0103452-02 £657.50/ea	£0.00	Quantity	£657.50/ea	£0.00

10 mgQM-0103452-03	10 mgQM-0103452-03 £1,022.00/ea	£0.00	Quantity	£1,022.00/ea	£0.00

25 mgQM-0103452-04	25 mgQM-0103452-04 £1,994.00/ea	£0.00	Quantity	£1,994.00/ea	£0.00

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TNF-α-IN-19 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.