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TNKS-IN-4 [CAS 1507362-06-2]

TNKS-IN-4 [CAS 1507362-06-2]

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SKU:QM-0005261

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  • Description

    TNKS-IN-4 (compound 49) is an orally active tankyrase (TNKS) inhibitor with IC50 values of 0.1 nM and 7.6nM for TNKS1 and TNKS2, respectively. TNKS-IN-4 can be used for study of APC-mutant colorectal cancer[1].

  • CAS Number

    [1507362-06-2]

  • Molecular Formula

    C24H24N4O3S

  • Molecular Weight

    448.54

  • Smiles

    O=C1C2=CC=CC=C2NC(SCCC(N[C@@H]3CC[C@@H](OC4=CC=C(C#N)C=C4)CC3)=O)=N1

  • Target

    PARP

  • Isoform

    TNKS1/PARP5A; TNKS2/PARP5B

  • Shipping Conditions

    Room temperature

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TNKS-IN-4 [CAS 1507362-06-2]

TNKS-IN-4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.